赵宏(研究员)
赵宏(研究员)的个人简介
赵宏,工学博士,北京化工大学研究员。专业方向为化工过程强化,节能环保技术等。
简介
先后担任国家“863”计划、“国家科技支撑计划”和“国家自然科学基金”等课题负责人。获全国优秀博士论文提名、北京市优秀博士论文奖、教育部技术发明奖一等奖、北京市科学技术奖一等奖等;
2009大学生年度人物百强入围、光电功能薄膜及其应用性能基础研究2012年度中国石油和化学工业联合会科技进步二等奖。
完成了全球首条40000 公斤/年纳米抗生素示范生产线和5000吨/年纳微结构维生素生产线的设计、建设,年产值超过10亿元,产品远销海内外;负责完成了多条大型超重力脱硫、脱碳装置的设计、运行、调试工作,负责建成了全球首套海洋平台脱硫核心反应器。获 “中国石油和化学工业联合会”科技成果鉴定等。在“Advanced Materials”作为第一作者发表封面文章;在 “Small” 、“Ind. Eng. Chem. & Res.”等国内外重要期刊上发表SCI论文等30余篇,发明专利20余件,国际发明专利2件。
学术论文
[1] Zhao H, Chen J-F, Zhao Y, Jiang L, Sun J-W, Yun J. Hierarchical Assembly of Multilayered Hollow Microspheres from an Amphiphilic Pharmaceutical Molecule of Azithromycin[J]. Advanced Materials, 2008, 20(19): 3682-3686. (SCI; IF=13.877)
[2] Zhao H, Shao L, Chen J-F. High-Gravity Process Intensification Technology and Application[J]. Chemical Engineering Journal, 2010, 156(3):588-593. (SCI; IF=3.813)
[3] Zhao H, Wang J X, Wang Q A, Chen J-F, Yun J. Controlled Liquid Antisolvent Precipitation of Hydrophobic Pharmaceutical Nanoparticles in a Microchannel Reactor[J]. Industrial & Engineering Chemistry Research, 2007, 46(24): 8229-8235. (SCI; IF=2.23)
[4] Zhao H, Le Y, Liu H-Y, Hu T-T, Shen Z-G, Chen J-F. Preparation of Microsized Spherical Aggregates of Ultrafine Ciprofloxacin Particles for Dry Powder Inhalation (DPI)[J]. Powder Technology, 2009, 194(1-2): 81-86. (SCI; IF=2.3)
[5] Zhao H, Wang J-X, Zhang H-X, Shen Z-G, Yun J, Chen J-F. Facile Preparation of Danazol Nanoparticles by High-Gravity Anti-solvent Precipitation (HGAP) Method[J]. Chinese Journal of Chemical Engineering, 2009, 17(2): 318-323. (SCI; IF=0.572)
[6] Zhao H, Kang X-L, Chen X-L, Wang J-X, Le Y, Shen Z-G, Chen J-F. Antibacterial Activities of Amorphous Cefuroxime Axetil Ultrafine Particles Prepared by High Gravity Antisolvent Precipitation (HGAP)[J]. Pharmaceutical Development and Technology, 2009, 14 (5): 485-491. (SCI; IF=1.36)
[7] Zhang H-X, Zhao H, Wang J-X, Chen J.-F., Lu Y.-F. and Yun J. Facile Preparation of Monodisperse Pharmaceutical Colloidal Spheres of Atorvastatin Calcium via Self-Assembly[J]. Small, 2009, 5(16): 1846-1849. (SCI; IF=8.349)
[8] Hu T-T, Zhao H, Jiang L-C, Le Y., Chen J.-F. and Yun J. Engineering Pharmaceutical Fine Particles of Budesonide for Dry Powder Inhalation (DPI)[J]. Industrial & Engineering Chemistry Research, 2008, 47(23): 9623-9627. (SCI; IF=2.23)
[9] Zhang Z-B, Shen Z-G, Wang J-X, Zhao H, Chen J-F, Yun J. Nanonization of Megestrol Acetate by Liquid Precipitation[J]. Industrial & Engineering Chemistry Research, 2009, 48(18): 8493-8499. (SCI; IF=2.23)
[10] Zhang Z-B, Shen Z-G, Wang J-X, Zhang H-X, Zhao H, Chen J-F, Yun J. Micronization of Silybin by the Emulsion Solvent Diffusion Method[J]. International Journal of Pharmaceutics, 2009, 376(1-2): 116-122. (SCI; IF=3.35)
[11] Wang J-X, Zhang Z-B, Le Y, Zhao H, Chen J-F. A Novel Strategy to Produce Highly Stable and Transparent Aqueous ’Nanosolutions’ of Water-Insoluble Drug Molecules[J]. Nanotechnology, 2011, 22(30): 305101. (SCI; IF=3.35)
[12] Xu L-M, Zhang Q-X, Zhou Y, Zhao H, Wang J-X, Chen J-F. Engineering Drug Ultrafine Particles of Beclomethasone Dipropionate for Dry Powder Inhalation[J]. International Journal of Pharmaceutics, 2012, 436(1-2): 1-9. (SCI, IF=3.35)
[13] Zhang X-P, Le Y, Wang J-X, Zhao H, Chen J-F. Resveratrol Nanodispersion with High Stability and Dissolution Rate[J]. WT-FOOD SCIENCE AND TECHNOLOGY, 2013, 50(2): 622-628. (SCI, IF=2.546)
[14] Liu H-T, Zeng X-F, Zhao H, Chen J-F. Highly Transparent and Multifunctional Polymer Nanohybrid Film with Superhigh ZnO Content Synthesized by a Bulk Polymerization Method[J]. Industrial and Engineering Chemistry Research, 2012, 51(19): 6753-6759. (SCI, IF=2.206)
[15] Hou C-D, Wang J-X, Le Y, Zou H-K, Zhao H. Preparation of Azithromycin Nanosuspensions by Reactive Precipitation Method[J]. Drug Development and Industrial Pharmacy, 2012, 38(7): 848-854. (SCI, IF=1.539)
[16] Zhang Z-L, Le Y, Wang J-X, Zhao H, Chen J-F. Irbesartan Drug Formulated as Nanocomposite Particles for the Enhancement of the Dissolution Rate[J]. Particuology, 2012, 10(4): 462-467. (SCI, IF=1.419).
[17] Zhang Z-L, Le Y, Wang J-X, Zhao H, Chen J-F. Development of Stabilized Itraconazole Nanodispersions by Using High-gravity Technique[J]. Drug Development and Industrial Pharmacy, 2012, 38(12): 1512-1520. (SCI, IF=1.494).
[18] Yi Q-H, Chen J-F, Le Y, Wang J-X, Xue C-Y, Zhao H. Crystal Structure and Habit of Dirithromycin Acetone Solvate: A Combined Experimental and Simulative Study[J]. Journal of Crystal Growth, 2013, 372: 193-198. (SCI; IF=1.6)
[19] Liang Z-Z, Yi Q-H, Wang W, Han X-L, Chen J-F, Le Y, Wang J-X, Xue C-Y, Zhao H. A Systematic Study of Solvent Effect on the Crystal Habit of Dirithromycin Solvates by Computer Simulation[J]. Computer and Chemical Engineering, 2014, 62(0): 56-61. (SCI; IF=2.32)
[20] Liang Z-Z, Chen J-F, Ma Y, Wang W, Han X-L, Xue C-Y, Zhao H, Qualitative rationalization of crystal growth morphology of benzoic acid controlled using solvents[J]. CrystEngComm. 2014, 16(27): 5997-6002. (SCI; IF=3.842)
[21] Liang Z-Z, Wang W, Han X-L, Ma Y, Chen J-F, Xue C-Y, Zhao H, Regulation of Crystal Habit and Aspect Ratio of Benzoic Acid by Initial Supersaturation Control: A Combined Simulative and Experimental Study [J]. RSC Advances., 2014. (To be submitted)
[22] Liang Z-Z, Liu L, Wang W, Han X-L, Chen J-F, Xue C-Y, Zhao H, Mechanism of Clustered Aggregation of y-elongated Hexagonal Dirithromycin Crystals[J]. Chemical Communication. 2014. (To be submitted)
[23] 刘淼, 乐园, 赵宏, 杨宗阳, 陈建峰, 超细琥珀酸舒马普坦的制备及其性能评价, 化学反应工程与工艺[J], 2008, 24: 1-6.
[24] 胡婷婷, 乐园, 赵宏, 沈志刚, 陈建峰, 高压均质技术结合喷雾干燥法制备布地奈德多孔微球, 北京化工大学学报[J], 2009, 36(2): 9-13.
[25] 葛菲, 乐园, 赵宏, 王洁欣, 邵磊, 陈建峰, 不同形貌盐酸环丙沙星粉雾剂的制备及其性能研究, 现代化工[J],2009, 29(3): 57-59.
[26] 张海霞, 王洁欣, 王立新, 赵宏, 邵磊, 陈建峰, 反溶剂沉淀法制备阿托伐
他汀钙微粉, 化工学报[J], 2008, 59: 3132-3137.
[27] 崔改静, 周月, 段永鸿, 赵宏, 王洁欣, Y型微通道内聚乳酸-羟基乙酸共聚物纳米分散体的制备, 北京化工大学学报(自然科学版), 2012, 01: 58-62.
[28] 谢玉洁, 乐园, 王洁欣, 赵宏, 陈建峰, 反溶剂重结晶法制备青蒿素超细粉体, 化工学报, 2012, 63(5): 1607-1614.
[29] 张智亮, 陈艳雅, 乐园, 赵宏, 曾晓飞, 陈建峰, 超细药物晶体颗粒的制备及其溶出性能, 高校化学工程学报, 2011, 25(4): 656-661.
[30] 侯成栋, 王洁欣, 乐园, 赵宏, 陈建峰, 反应结晶法制备阿奇霉素纳米复合粉体, 现代化工, 2011, 31(增刊(1)): 107-109.
专利
[1] 陈建峰,赵宏,初广文,邹海魁,邵磊,余文,罗勇;一种连续式乳化装置及工艺方法:中国专利,CN 200810106136.5
[2] 陈建峰,赵宏,王洁欣,沈志刚,甄崇礼;一种超细达那唑粉体的制备方法:中国专利,CN 200710098804.X
[3] 陈建峰,胡婷婷,赵宏,初广文,王洁欣,乐园,沈志刚;一种纳微结构药物颗粒的制备方法及装置:中国专利,CN 200810223732.1
[4] 陈建峰,王哲,赵宏,王国联,王洁欣;一种利用微反应器制备微粉化药物的方法:中国专利,CN 200710063442.0
[5] 陈建峰,胡婷婷,赵宏,初广文,王洁欣,乐园,沈志刚;一种内循环旋转填充床超重力场装置:中国专利,CN 200820122788.3
[6] 陈建峰,张志兵,王洁欣,赵宏,沈志刚;一种纳微结构水飞蓟宾药物复合粉体及其制备方法:中国专利,CN 200910076989.3
[7] 陈志荣,陈建峰,尹红,赵宏,仇丹,石立芳,李建东,初广文,邵磊;纳米分散的高全反式类胡萝卜素微胶囊的制备方法:中国专利,CN 200910097063.2
[8] 陈志荣,陈建峰,尹红,赵宏,祁勇,石立芳,仇丹,初广文,邵磊;一种连续化纳米分散维生素A的制备方法:中国专利,CN 200910097064.7
[9] 陈建峰,鱼潇,初广文,罗勇,赵宏,邹海魁;一种贝克曼重排反应新方法:中国专利,CN 201010279349.5
[10] 陈建峰,邹海魁,初广文,赵宏,向阳;用于减压精馏的超重力装置及应用方法:中国专利,CN 201310348152.6 [11] 罗勇,桑乐,初广文,陈建峰,赵宏,邹海魁;一种合成气合成混合醇的方法: 中国专利,CN 201110354112.3 [12] 陈建峰,鱼潇,初广文,罗勇,赵宏,邹海魁;多功能用途的多级旋转填充床反应器装置及利用该装置进行多相多组分反应的方法:中国专利, CN 201310454946.0 [13] 陈建峰,张D,初广文,赵宏;一种基于原位温度调控的费托合成反应方法 :中国专利, CN 201210240350.6
[14] 陈建峰,王伟,邹海魁,初广文,赵宏; 一种制备溴化丁基橡胶的方法:中国专利, CN 201110266048.3 [15] 陈建峰,初广文,邹海魁,赵宏,罗勇; 一种低压降纳微结构化填料旋转床超重力装置及应用:中国专利, CN 201010579829.3 [16] 赵宏,陈建峰,罗勇,刘海涛,初广文,邹海魁;用于聚合物快速混合溶解的旋转床装置及方法一种超重力高效脱除NOX的装置及工艺:中国专利, CN 201310327376.9 [17] 陈建峰,孙宝昌,赵宏,初广文,罗勇,邹海魁;一种超重力高效脱除NOX的装置及工艺:中国专利, CN 201310499098.5 [18] 陈建峰,梁作中,赵宏,初广文,邹海魁,罗勇,孙宝昌;海上平台脱除低含量硫化氢原料气中的硫化氢的方法:中国专利,CN201310722429.7
[19] 初广文,桑乐,陈建峰,罗勇,邹海魁,赵宏;深度脱除工业尾气中氮氧化物的系统装置及方法:中国专利,CN201310356553.6
[20] 陈建峰,张亮亮,赵宏,王洁欣,张鹏远,初广文;一种快速制备驱油用聚合物溶液的方法:中国专利,CN201210555352.4
[21] 陈志荣,陈建峰,尹红,赵宏,祁勇,石立芳,仇丹,初广文,邵磊;连续化纳米分散维生素A微胶囊的制备方法:中国专利,CN200910097064.7
[22] 陈建峰,孙佳奇,陈志荣,赵宏,尹红,祁勇,石立芳,初广文;超重力法制备纳米维生素E水分散粉体制剂的方法:中国专利,CN201010151522.3